Transdiagnostic neuroimaging of reward system phenotypes in ADHD and comorbid disorders

• We synthesize ADHD neuroimaging findings on the reward system with in obesity, depression, and substance use disorder. analyze from monetary incentive delay (MID) discounting (DD) tasks, striatal connectivity volumetry. discuss these features ADHD, depression disorder ask whether heterogeneity comorbidity are reflected by a common dysregulation system. highlight conceptual issues related to heterogeneous paradigms, different phenotyping, longitudinal prediction. is characterized changes which highly comorbid other mental disorders, suggesting neurobiological pathways. Transdiagnostic could help understand dysregulated pathway might be actual link between its comorbidities. here including their appearance regarding neuroanatomical (structural MRI) activation patterns (resting-state functional MRI). focus monetary-incentive-delay delay-discounting tasks then review data Next, for better understanding of adult we Finally, prediction some promising future directions using functioning as clinical biomarker.